Angular Material autocomplete infinite scroll with $http request

I guess we need go with custom directive for your requirement.

I have created directive which actually binds scroll event on "md-virtual-repeat-container" which holds the items list after rendering.

JS

Your directive will be like below. Purpose of this directive is get scroll event and call attached function when user reach at the end of scroll. Condition "new Date().getTime() - now > 100" will acts as a throttle API call. You can change throttle time from 100 milli sec to any ms if you want to limit your API calls between 100 milli sec of user action.

.directive('lazyLoadData', function($compile) {
     return {
         link: function(scope, el, attrs) {
            var now = new Date().getTime();
            var rep = angular.element(document.getElementsByClassName("md-virtual-repeat-scroller"));
            rep.on('scroll', function(evt){
               if (rep[0].scrollTop + rep[0].offsetHeight >= rep[0].scrollHeight)
                  if (new Date().getTime() - now > 1000) {                  
                     now = new Date().getTime();
                     scope.$apply(function() { 
                        scope.$eval(attrs.lazyLoadData); 
                     });
                  }                  
            });
         }
    }; 
});

HTML Your html will like as below,

<md-autocomplete flex
                 md-selected-item="ctrl.selectedItem"
                 md-search-text="searchText"
                 md-items="item in querySearch(searchText)"
                 md-item-text="item.login"
                 md-delay="300"
                 md-floating-label="Search Github Users"
                 lazy-load-data="querySearch()" <!--New directive will go here -->
>
   <div layout="row" class="item" layout-align="start center">
      <img ng-src="{{item.avatar_url}}" class="avatar" />
      &nbsp;&nbsp;
      <span md-highlight-text="searchText">{{item.login}}</span>  
   </div>
</md-autocomplete>

Here is DEMO

*Please note currently i am appending same data to my records array because i dont have actual API. But you can extend your API to get paged records based on searched text. Refer https://github.com/davidchin/angular-endless-scroll OR http://www.dotnetawesome.com/2016/03/infinite-scroll-for-facebook-like-pagination-angularjs.html