ASP.Net MissingMethodException - "ctor" method not found

If you see this error happening on a site that has custom errors turned on, then the error is happening in the custom error handling routine itself.

From the look of the .NET error message it appears that your routine is expecting a constructor that accepts an exception by reference - your comment above shows a constructor that accepts by value.

Check carefully that there isn't a stale version of an assembly in your system somewhere. These can lurk in the Temporary ASP.NET Files folder; you'll need to do an "iisreset /stop" before you can clear them out.

In that regard it's always a good idea to make sure that AssemblyInfo.cs is set up to automatically stamp version numbers in some way. We have our version numbers tied to our source code repository system and CI build box so we can tell exactly what was in what assembly really easily.

I would use elmah: http://code.google.com/p/elmah/ to hopefully give you a bit more insight into the issue. It is free and can be used on an existing site without any recompilation. Try it - and post back if the issue is still happening.

As others have also mentioned, I would suspect that your site is somehow using an out of date version of an assembly. Something you could try doing is a full Precompile of your site before deploying to your production server. This ensures that ASP .Net doesn't dynamically compile the site on the fly, and therefore should mean that it's using completely up to date code throughout.