asp.net mvc dropdownlist option disabled selected

Unfortunately not. There is no way to add attributes to a SelectListItem, which is what gets rendered as an <option>.

You would need to extend the SelectListItem class, and then extend the DropDownListFor to use it. It is unfortunately not very straightforward... It would have been nice for there to be an Attributes dictionary on SelectListItem for this purpose.

Here is an implementation of a custom attribute being applied:

Adding html class tag under <option> in Html.DropDownList