Can Flask have optional URL parameters?

Almost the same as Audrius cooked up some months ago, but you might find it a bit more readable with the defaults in the function head - the way you are used to with python:

@app.route('/<user_id>')
@app.route('/<user_id>/<username>')
def show(user_id, username='Anonymous'):
    return user_id + ':' + username

Another way is to write

@user.route('/<user_id>', defaults={'username': None})
@user.route('/<user_id>/<username>')
def show(user_id, username):
    pass

But I guess that you want to write a single route and mark username as optional? If that's the case, I don't think it's possible.