change <audio> src with javascript

Try this snippet

list.onclick = function(e) {
  e.preventDefault();

  var elm = e.target;
  var audio = document.getElementById('audio');

  var source = document.getElementById('audioSource');
  source.src = elm.getAttribute('data-value');

  audio.load(); //call this to just preload the audio without playing
  audio.play(); //call this to play the song right away
};
<ul style="list-style: none">
  <li>Audio Files
    <ul id="list">
      <li><a href="#" data-value="http://media.w3.org/2010/07/bunny/04-Death_Becomes_Fur.oga">Death_Becomes_Fur.oga</a></li>
      <li><a href="#" data-value="http://media.w3.org/2010/07/bunny/04-Death_Becomes_Fur.mp4">Death_Becomes_Fur.mp4</a></li>
      <li><a href="#" data-value="http://media.w3.org/2010/11/rrs006.oga">rrs006.oga</a></li>
      <li><a href="#" data-value="http://media.w3.org/2010/05/sound/sound_90.mp3">sound_90.mp3</a></li>
    </ul>
  </li>
</ul>

<audio id="audio" controls="controls">
  <source id="audioSource" src=""></source>
  Your browser does not support the audio format.
</audio>

JSFiddle http://jsfiddle.net/jm6ky/2/


with jQuery:

 $("#playerSource").attr("src", "new_src");

    var audio = $("#player");      

    audio[0].pause();
    audio[0].load();//suspends and restores all audio element

    if (isAutoplay) 
        audio[0].play();