Change color of Button when Mouse is over

<Button Content="Click" Width="200" Height="50">
<Button.Style>
    <Style TargetType="{x:Type Button}">
        <Setter Property="Background" Value="LightBlue" />
        <Setter Property="Template">
            <Setter.Value>
                <ControlTemplate TargetType="{x:Type Button}">
                    <Border x:Name="Border" Background="{TemplateBinding Background}">
                        <ContentPresenter HorizontalAlignment="Center" VerticalAlignment="Center" />
                    </Border>
                    <ControlTemplate.Triggers>
                        <Trigger Property="IsMouseOver" Value="True">
                            <Setter Property="Background" Value="LightGreen" TargetName="Border" />
                        </Trigger>
                    </ControlTemplate.Triggers>
                </ControlTemplate>
            </Setter.Value>
        </Setter>
    </Style>
</Button.Style>

As others already said, there seems to be no good solution to do that easily.
But to keep your code clean I suggest creating a seperate class that hides the ugly XAML.

How to use after we created the ButtonEx-class:

<Window x:Class="MyApp.MainWindow"
        xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
        xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
        xmlns:d="http://schemas.microsoft.com/expression/blend/2008"
        xmlns:mc="http://schemas.openxmlformats.org/markup-compatibility/2006"
        xmlns:wpfEx="clr-namespace:WpfExtensions"
        mc:Ignorable="d"
        Title="MainWindow" Height="450" Width="800">
    <Grid>
        <wpfEx:ButtonEx HoverBackground="Red"></wpfEx:ButtonEx>
    </Grid>
</Window>

ButtonEx.xaml.cs

using System.Windows;
using System.Windows.Controls;
using System.Windows.Media;

namespace WpfExtensions
{
    /// <summary>
    /// Standard button with extensions
    /// </summary>
    public partial class ButtonEx : Button
    {
        readonly static Brush DefaultHoverBackgroundValue = new BrushConverter().ConvertFromString("#FFBEE6FD") as Brush;

        public ButtonEx()
        {
            InitializeComponent();
        }

        public Brush HoverBackground
        {
            get { return (Brush)GetValue(HoverBackgroundProperty); }
            set { SetValue(HoverBackgroundProperty, value); }
        }
        public static readonly DependencyProperty HoverBackgroundProperty = DependencyProperty.Register(
          "HoverBackground", typeof(Brush), typeof(ButtonEx), new PropertyMetadata(DefaultHoverBackgroundValue));
    }
}

ButtonEx.xaml
Note: This contains all the original XAML from System.Windows.Controls.Button

<Button x:Class="WpfExtensions.ButtonEx"
             xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
             xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
             xmlns:mc="http://schemas.openxmlformats.org/markup-compatibility/2006" 
             xmlns:d="http://schemas.microsoft.com/expression/blend/2008" 
             mc:Ignorable="d" 
             d:DesignHeight="450" d:DesignWidth="800"
            x:Name="buttonExtension">
    <Button.Resources>
        <Style x:Key="FocusVisual">
            <Setter Property="Control.Template">
                <Setter.Value>
                    <ControlTemplate>
                        <Rectangle Margin="2" SnapsToDevicePixels="true" Stroke="{DynamicResource {x:Static SystemColors.ControlTextBrushKey}}" StrokeThickness="10" StrokeDashArray="1 2"/>
                    </ControlTemplate>
                </Setter.Value>
            </Setter>
        </Style>
        <SolidColorBrush x:Key="Button.Static.Background" Color="#FFDDDDDD"/>
        <SolidColorBrush x:Key="Button.Static.Border" Color="#FF707070"/>
        <SolidColorBrush x:Key="Button.MouseOver.Background" Color="#FFBEE6FD"/>
        <SolidColorBrush x:Key="Button.MouseOver.Border" Color="#FF3C7FB1"/>
        <SolidColorBrush x:Key="Button.Pressed.Background" Color="#FFC4E5F6"/>
        <SolidColorBrush x:Key="Button.Pressed.Border" Color="#FF2C628B"/>
        <SolidColorBrush x:Key="Button.Disabled.Background" Color="#FFF4F4F4"/>
        <SolidColorBrush x:Key="Button.Disabled.Border" Color="#FFADB2B5"/>
        <SolidColorBrush x:Key="Button.Disabled.Foreground" Color="#FF838383"/>
    </Button.Resources>
    <Button.Style>
        <Style TargetType="{x:Type Button}">
            <Setter Property="FocusVisualStyle" Value="{StaticResource FocusVisual}"/>
            <Setter Property="Background" Value="{StaticResource Button.Static.Background}"/>
            <Setter Property="BorderBrush" Value="{StaticResource Button.Static.Border}"/>
            <Setter Property="Foreground" Value="{DynamicResource {x:Static SystemColors.ControlTextBrushKey}}"/>
            <Setter Property="BorderThickness" Value="1"/>
            <Setter Property="HorizontalContentAlignment" Value="Center"/>
            <Setter Property="VerticalContentAlignment" Value="Center"/>
            <Setter Property="Padding" Value="1"/>
            <Setter Property="Template">
                <Setter.Value>
                    <ControlTemplate TargetType="{x:Type Button}">
                        <Border x:Name="border" BorderBrush="{TemplateBinding BorderBrush}" BorderThickness="{TemplateBinding BorderThickness}" Background="{TemplateBinding Background}" SnapsToDevicePixels="true">
                            <ContentPresenter x:Name="contentPresenter" Focusable="False" HorizontalAlignment="{TemplateBinding HorizontalContentAlignment}" Margin="{TemplateBinding Padding}" RecognizesAccessKey="True" SnapsToDevicePixels="{TemplateBinding SnapsToDevicePixels}" VerticalAlignment="{TemplateBinding VerticalContentAlignment}"/>
                        </Border>
                        <ControlTemplate.Triggers>
                            <Trigger Property="IsDefaulted" Value="true">
                                <Setter Property="BorderBrush" TargetName="border" Value="{DynamicResource {x:Static SystemColors.HighlightBrushKey}}"/>
                            </Trigger>
                            <Trigger Property="IsMouseOver" Value="true">
                                <Setter Property="Background" TargetName="border" Value="{Binding Path=HoverBackground, ElementName=buttonExtension}"/>
                                <Setter Property="BorderBrush" TargetName="border" Value="{StaticResource Button.MouseOver.Border}"/>
                            </Trigger>
                            <Trigger Property="IsPressed" Value="true">
                                <Setter Property="Background" TargetName="border" Value="{StaticResource Button.Pressed.Background}"/>
                                <Setter Property="BorderBrush" TargetName="border" Value="{StaticResource Button.Pressed.Border}"/>
                            </Trigger>
                            <Trigger Property="IsEnabled" Value="false">
                                <Setter Property="Background" TargetName="border" Value="{StaticResource Button.Disabled.Background}"/>
                                <Setter Property="BorderBrush" TargetName="border" Value="{StaticResource Button.Disabled.Border}"/>
                                <Setter Property="TextElement.Foreground" TargetName="contentPresenter" Value="{StaticResource Button.Disabled.Foreground}"/>
                            </Trigger>
                        </ControlTemplate.Triggers>
                    </ControlTemplate>
                </Setter.Value>
            </Setter>
        </Style>
    </Button.Style>
</Button>

Tip: You can add an UserControl with name "ButtonEx" to your project in VS Studio and then copy paste the stuff above in.

Try this- In this example Original color is green and mouseover color will be DarkGoldenrod

<Button Content="Button" HorizontalAlignment="Left" VerticalAlignment="Bottom" Width="50" Height="50" HorizontalContentAlignment="Left" BorderBrush="{x:Null}" Foreground="{x:Null}" Margin="50,0,0,0">
    <Button.Style>
        <Style TargetType="{x:Type Button}">
            <Setter Property="Background" Value="Green"/>
            <Setter Property="Template">
                <Setter.Value>
                    <ControlTemplate TargetType="{x:Type Button}">
                        <Border Background="{TemplateBinding Background}">
                            <ContentPresenter HorizontalAlignment="Center" VerticalAlignment="Center"/>
                        </Border>
                    </ControlTemplate>
                </Setter.Value>
            </Setter>
            <Style.Triggers>
                <Trigger Property="IsMouseOver" Value="True">
                    <Setter Property="Background" Value="DarkGoldenrod"/>
                </Trigger>
            </Style.Triggers>
        </Style>
    </Button.Style>
</Button>