Change CTRL-X, -C, and -V hotkeys in Windows to different keys

You can use AutoHotkey to assign the same function to another combo. The benefit is that the old ones will still work as well so if someone else uses your machine it wont throw them off:

^m::^x
^,::^c
^.::^v

You might be interested to learn that there are alternative hotkeys available:

• Copy: Ctrl+Ins
• Cut: Shift+Del
• Paste: Shift+Ins

These hotkeys seem to have been derived from the IBM CUA. However, I don't know if they were specifically chosen for left-handed users.