Conditions for positive definiteness: matrix inequality
Hint:
Rewrite it as should be positive definite as you desired:
$$Sc \triangleq \Big (I_n - \frac{1}{\alpha}B^T B \Big )- \frac{1}{4\alpha (1-\alpha)}\Big\{(A^TB+A)^T I_n (A^TB+A)\Big \} \succ 0$$
Then, by using Schur complement, $S_c$ is positive definite if and only if the matrix $S$ defined as:
$$S \triangleq \begin{pmatrix} \frac{1}{4\alpha (1-\alpha)}I_n & A^TB+A \\ (A^TB+A)^T & I_n - \frac{1}{\alpha}B^T B \end{pmatrix},$$
is:
$$S \succ 0 \quad \text{with the conditions mentioned below would be satisfied.} $$ Also, we have:
$$ \lambda_i(S) >0; \quad \text{for all } i = 0,1, ..., n.$$
Now, it needs to check for which $A$ and $B$ the above relationship (Schur complement) can be satisfied.
Second, is to show the eigenvalues of such block matrix is positive.
Side note: Schur complement
For any symmetric matrix X, of the form:
$$X \triangleq \begin{pmatrix} A & B \\ B^T & C \end{pmatrix},$$
if $A$ is invertible, then the following statement holds:
$X \succ 0$ if and only if $A \succ 0$ and $C-B^T A^{-1} B \succ 0.$