css variables manipulate with js code example

Example 1: how to change a css variable with javascript

var root = document.querySelector(':root');
root.style.setProperty('--variable', 'lightblue');
/or/
root.style.setProperty('--variable', myColor);

Example 2: change css variable with javascript

let root = document.documentElement;

root.addEventListener("mousemove", e => {
  root.style.setProperty('--mouse-x', e.clientX + "px");
  root.style.setProperty('--mouse-y', e.clientY + "px");
});