How to align items cemter in flexbox code example

Example 1: center div css flex

section {
  width: 200px;
  border: 1px solid #2d2d2d;
  display: flex;
  justify-content: center;
}

Example 2: css center image horizontal and vertical flexbox

<!doctype html>
<html lang="en">
<head>
  <meta charset="utf-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <title>Center Flex Item Image</title>
<style>
.box {
   width:80%;
   min-height:80vh;
   margin:auto;
   border:1px solid;
   display: flex;
   align-items: center;
   justify-content: center; /* not really needed with auto margin on img*/
}
.box img {
   display: block;
   width: 80%;
   min-width:100px;
   max-width: 350px; /*actual image width*/
   height: auto; /* maintain aspect ratio*/
   margin: auto; /*optional centering of image*/
}
</style>

</head>
<body>

<div class="box">
   <img src="http://via.placeholder.com/350x250" width="350" height="250" alt="missing image">
</div>

</body>
</html>

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