Delete a subplot

Use fig.delaxes or plt.delaxes to remove unwanted subplots

fig, axs = plt.subplots(1,3)
axs[0].plot([1,2],[3,4])
axs[2].plot([0,1],[2,3])

fig.delaxes(axs[1])

plt.draw()
plt.tight_layout()

enter image description here

ax.set_visible(False)

will suffice in most cases.

Remove the axis from the figure doc:

axs[1].remove()

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