Determine if Python variable is an instance of a built-in type

The best way to achieve this is to collect the types in a list of tuple called primitiveTypes and:

if isinstance(myvar, primitiveTypes): ...

The types module contains collections of all important types which can help to build the list/tuple.

Works since Python 2.2

This is an old question but it seems none of the answers actually answer the specific question: "(How-to) Determine if Python variable is an instance of a built-in type". Note that it's not "[...] of a specific/given built-in type" but of a.

The proper way to determine if a given object is an instance of a buil-in type/class is to check if the type of the object happens to be defined in the module __builtin__.

def is_builtin_class_instance(obj):
    return obj.__class__.__module__ == '__builtin__'

Warning: if obj is a class and not an instance, no matter if that class is built-in or not, True will be returned since a class is also an object, an instance of type (i.e. AnyClass.__class__ is type).