Disable hover information on trace, plotly

A more general-purpose solution may be to set the Layout 'hovermode' property, as follows:

#...
layout = go.Layout(hovermode=False)
fig = go.Figure(data=data, layout=layout)
#...

Reference for Python here: https://plot.ly/python/reference/#layout

NB: This will disable hover text for all traces associated with that layout... May not be the desired behaviour.

On your trace add: hoverinfo='skip'

trace = dict(
             x=[1,2,3,4],
             y=[1,2,3,4],
             hoverinfo='skip'
            )

from plotly.offline import plot
import plotly.graph_objs as go

def spline(x_axis,loop):

     trace = go.Scatter(
        x = x_axis,
        y = loop[i],
        fill = 'tonexty',
        mode ='lines',
        showlegend = False,
        hoverinfo='none'
        )

    data = [trace]



    layout = go.Layout(
        title='Graph title here',
        height=600,
        xaxis=dict(
            autorange=True
        ),
        yaxis=dict(
            autorange=True
        )
    )
    fig = go.Figure(data=data, layout=layout)
    # plot(fig, filename='spline.html')
    plot_div = plot(fig, output_type='div', include_plotlyjs=False)
    return plot_div