empty selection on change select2 code example
Example 1: select2 clear options
Remove the selected options :
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$('#mySelect2').val(null).trigger('change');
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Completly remove the select2 initialization :
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$('#payment_method').html('').select2({data: [{id: '', text: ''}]});
Example 2: select2 dropdown with option to add new item
$('#select2')
.select2()
.on('select2:open', () => {
$(".select2-results:not(:has(a))").append('Create new item');
})