how can I enable scrollbars on the WPF Datagrid?

WPF4

<DataGrid AutoGenerateColumns="True" Grid.Column="0" Grid.Row="0"
      ScrollViewer.CanContentScroll="True" 
      ScrollViewer.VerticalScrollBarVisibility="Auto"
      ScrollViewer.HorizontalScrollBarVisibility="Auto">
</DataGrid>

with : <ColumnDefinition Width="350" /> & <RowDefinition Height="300" /> works fine.

Scrollbars don't show with <ColumnDefinition Width="Auto" /> & <RowDefinition Height="300" />.

Also works fine with: <ColumnDefinition Width="*" /> & <RowDefinition Height="300" /> in the case where this is nested within an outer <Grid>.

Put the DataGrid in a Grid, DockPanel, ContentControl or directly in the Window. A vertically-oriented StackPanel will give its children whatever vertical space they ask for - even if that means it is rendered out of view.