How can I remove numbers, and words with length below 2, from a sentence?

You may use:

s = re.sub(r'\b(?:\d+|\w)\b\s*', '', s)

RegEx Demo

Pattern Details:

• \b: Match word boundary
• (?:\d+|\w): Match a single word character or 1+ digits
• \b: Match word boundary
• \s*: Match 0 or more whitespaces