How can I reset a react component including all transitively reachable state?

You should actually avoid replaceState and use setState instead.

The docs say that replaceState "may be removed entirely in a future version of React." I think it will most definitely be removed because replaceState doesn't really jive with the philosophy of React. It facilitates making a React component begin to feel kinda swiss knife-y. This grates against the natural growth of a React component of becoming smaller, and more purpose-made.

In React, if you have to err on generalization or specialization: aim for specialization. As a corollary, the state tree for your component should have a certain parsimony (it's fine to tastefully break this rule if you're scaffolding out a brand-spanking new product though).

Anyway this is how you do it. Similar to Ben's (accepted) answer above, but like this:

this.setState(this.getInitialState());

Also (like Ben also said) in order to reset the "browser state" you need to remove that DOM node. Harness the power of the vdom and use a new key prop for that component. The new render will replace that component wholesale.

Reference: https://facebook.github.io/react/docs/component-api.html#replacestate

Adding a key attribute to the element that you need to reinitialize, will reload it every time the props or state associate to the element change.

key={new Date().getTime()}

Here is an example:

render() {
  const items = (this.props.resources) || [];
  const totalNumberOfItems = (this.props.resources.noOfItems) || 0;

  return (
    <div className="items-container">
      <PaginationContainer
        key={new Date().getTime()}
        totalNumberOfItems={totalNumberOfItems}
        items={items}
        onPageChange={this.onPageChange}
      />
    </div>
  );
}

To ensure that the implicit browser state you mention and state of children is reset, you can add a key attribute to the root-level component returned by render; when it changes, that component will be thrown away and created from scratch.

render: function() {
    // ...
    return <div key={uniqueId}>
        {children}
    </div>;
}

There's no shortcut to reset the individual component's local state.