How do I find the nearest prime number?

Rather than a sorted list of primes, given the relatively small range targetted, have an array indexed by all the odd numbers in the range (you know there are no even primes except the special case of 2) and containing the closest prime. Finding the solution becomes O(1) time-wise.

I think the 100th prime is circa 541. an array of 270 [small] ints is all that is needed.

This approach is particularly valid, given the relative high density of primes (in particular relative to odd numbers), in the range below 1,000. (As this affects the size of a binary tree)

If you only need to search in the first 100 primes or so, just create a sorted table of those primes, and do a binary search. This will either get you to one prime number, or a spot between two, and you check which of those is closer.

Edit: Given the distribution of primes in that range, you could probably speed things up (a tiny bit) by using an interpolation search -- instead of always starting at the middle of the table, use linear interpolation to guess at a more accurate starting point. The 100th prime number should be somewhere around 250 or so (at a guess -- I haven't checked), so if (for example) you wanted the one closest to 50, you'd start about 1/5th of the way into the array instead of halfway. You can pretty much treat the primes as starting at 1, so just divide the number you want by the largest in your range to get a guess at the starting point.