How do I get help messages to appear for my Powershell script parameters?

Apparently if you have a help header defined, you can just use a remark (#) behind the parameter (in this example: #The targets to run.):

<#
.SYNOPSIS
    .
.DESCRIPTION
    .
.PARAMETER Path
    The path to the .
.PARAMETER LiteralPath
    Specifies a path to one or more locations. Unlike Path, the value of 
    LiteralPath is used exactly as it is typed. No characters are interpreted 
    as wildcards. If the path includes escape characters, enclose it in single
    quotation marks. Single quotation marks tell Windows PowerShell not to 
    interpret any characters as escape sequences.
#>

Param(
    [String]$Targets = "Help"   #The targets to run.
)

Results in:

PS C:\> Get-help .\Setup.ps1 -Detailed

NAME
    C:\Setup.ps1

SYNOPSIS
    .


SYNTAX
    C:\Setup.ps1 [[-Targets] <String>] [<CommonParameters>]


DESCRIPTION
    .


PARAMETERS
    -Targets <String>
        The targets to run.

You put a certain style of comment at the top of the file that can be decoded by the PowerShell help system. Here's an example:

<#
.SYNOPSIS
    .
.DESCRIPTION
    .
.PARAMETER Path
    The path to the .
.PARAMETER LiteralPath
    Specifies a path to one or more locations. Unlike Path, the value of 
    LiteralPath is used exactly as it is typed. No characters are interpreted 
    as wildcards. If the path includes escape characters, enclose it in single
    quotation marks. Single quotation marks tell Windows PowerShell not to 
    interpret any characters as escape sequences.
.EXAMPLE
    C:\PS> 
    <Description of example>
.NOTES
    Author: Keith Hill
    Date:   June 28, 2010    
#>
function AdvFuncToProcessPaths
{
    [CmdletBinding(DefaultParameterSetName="Path")]
    param(
        [Parameter(Mandatory=$true, Position=0, ParameterSetName="Path", 
                   ValueFromPipeline=$true, 
                   ValueFromPipelineByPropertyName=$true,
                   HelpMessage="Path to ...")]
        [ValidateNotNullOrEmpty()]
        [string[]]
        $Path,

        [Alias("PSPath")]
        [Parameter(Mandatory=$true, Position=0, ParameterSetName="LiteralPath", 
                   ValueFromPipelineByPropertyName=$true,
                   HelpMessage="Path to ...")]
        [ValidateNotNullOrEmpty()]
        [string[]]
        $LiteralPath
    )
    ...

For more info see the help topic - man about_comment_based_help.