How do I update a Python package?

The best way I've found is to run this command from terminal

sudo pip install [package_name] --upgrade

sudo will ask to enter your root password to confirm the action.

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Note: Some users may have pip3 installed instead. In that case, use

sudo pip3 install [package_name] --upgrade

You might want to look into a Python package manager like pip. If you don't want to use a Python package manager, you should be able to download M2Crypto and build/compile/install over the old installation.