How do you use FogBugz with an Agile methodology?
As eed3si9n said, if you are consistent in your estimates for EBS, FogBugz will take care of this for you.
As to the more general, how does FogBugz fit with the Agile methodology, your best bet is to do sprints as mini-releases. Create a sprint and add the cases you want to achieve for that sprint to that release (or milestone). Give it an end date, say a week away, if you do week long sprints. Then EBS can track it and tell you if you are on schedule.
The graphs in the Reports section will also show you a burndown chart. The terminology is a bit different because FogBugz isn't Agile-only but the info is there.
You want to see if the expected time you are going to finish your sprint is staying steady or going forward. If it is steady you are on track and your burndown rate is on target. If it is creeping up, you are losing ground and your sprint is getting delayed. Time to move things to the next sprint or figure out why you messed up your estimates :)
Essentially I suppose this is a burn-up chart instead of a burndown chart, but it gives you the same answer to the same question. Am I going to finish on time? What do I have left to do?
Atalasoft's Lou Franco wrote an excellent post on this as well. Patrick Altman also has an article.
Update: fixed link to Altman's article
I asked the FogBugz guys the same thing because in XP for example you'd provide the estimate in IET (ideal engineering time). Their answer was to be consistent in the way you provide the estimate.