How to run current line in Spyder 3.5( ctrl +f10 not working)

Coming from R studio I imagine you were hoping to have a command that runs the next command, rather than just that one row (which can break a command into several parts and cause errors).

The exact equivalent doesn't exist yet but if you get accustomed to adding #%% before and after chunks ("cells") you want to run together then you can use the following commands to run the whole chunk.

Run cell: Ctrl + Return
Run cell and advance : Shift+Return

The key to run the current line by itself is F9. The shortcut ctrl+F10 is used if you are in debugging mode.

You can see a list of shortcuts by selecting Preferences in the Tool menu, and then clicking on Keyboard shortcuts.