How to use no fill for background color of a excel cell using c#?

Assuming that you want to achieve the same state as a cell's initial state (in a new worksheet), use this:

xlRange.Interior.ColorIndex = 0;

Try this:

xlRange.Interior.Pattern = Excel.Constants.xlNone;
xlRange.Interior.TintAndShade = 0;
xlRange.Interior.PatternTintAndShade = 0;

Maybe this is just partly related to this question; but I noticed by using

xlRange.Interior.Pattern = Excel.XlPattern.xlPatternNone;;

Also all cell fill color disappears. This is not the case when using:

xlRange.Interior.Pattern = Excel.XlPattern.xlPatternAutomatic;

I was searching for this and came upon this question, so I add this for extra info.

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