Hyperlinks are staying inactive after setting isEnabled=true to parent control

I hit the same issue.

What I did is to bind HyperLink's IsEnabled to the parent, and put that in an App global resource.

<Style TargetType="{x:Type Hyperlink}">
    <Setter Property="IsEnabled" Value="{Binding IsEnabled, RelativeSource={RelativeSource FindAncestor, AncestorType={x:Type FrameworkElement}}}" />
</Style>

I found the answer for my case of the hyperlink not getting re-enabled, not sure if it applies to yours:

I found that when the Hyperlink's parent control is disabled (IsEnabled=false), the Hyperlink will not get notified of changes, e.g. IsEnabledChanged does not get fired, even when the bound property changes value.

My solution was to change my Xaml to no longer disable the ancestor control (which was causing the Hyperlink's parent to be disabled). With the parent (TextBlock) always enabled, now Hyperlink updates properly always.

(I'm a little bothered that the IsEnabled binding behaves differently than Controls do, and I'm not sure what I would do if I couldn't leave the ancestor enabled... but at least this lets me understand the issue I was having, and lets me work around it.)

Details: WPF 3.5 SP1