If $A \subseteq \mathbb{N}$, $2^n \in A$ and if $x\in A$, then $\lfloor \sqrt{x} \rfloor \in A$. Is it true that $A=\mathbb{N}$?
Let's take one number $n$ which is not a power of $2$ and assume it is not in $A$.
If $n$ is not in $A$ then any number between $n^2$ and $(n+1)^2-1$ must be missing, because if one of these numbers is in $A$ then $n$ is in $A$, because the floor of the square root of all of them is equal to $n$.
Now, we can consider two steps. It is easy to see that all the numbers from $n^4$ to $(n+1)^4-1$ should be missing, otherwise in two steps we reach $n$.
Proceeding in this way we can see that all the numbers from $n^\alpha$ to $(n+1)^\alpha-1$ must be missing, where $\alpha$ is a power of 2.
Now, the ratio $\frac{n+1}{n}$ is larger than $1$, so there will be a value $\alpha$ such that $(n+1)^\alpha > 2\cdot n^\alpha$, i.e., that the range of forbidden numbers contains at least one number $m=n^\alpha$ and twice that number $2m=2n^\alpha$.
But it is easy to see that between a number $m$ which is not a power of two and its double $2m$ there is always a power of 2.
But this would imply that that power of 2 is forbidden, but this is a contradiction because all the powers of 2 are in $A$.
EDIT. The argument should work also if we know that $3^k\in A$ (or other powers with a fixed base). Indeed the ratio between $n^\alpha$ and $(n+1)^\alpha$ can always become large enough to be sure that a power of the base is inside the interval.
It's sufficient to show $$\forall n\in \mathbb N\quad \exists k,m\in \mathbb N \quad \text{s.t} \quad n^{2^k}<2^m<(n+1)^{2^k}$$
and it's equal to say $$\forall n\in \mathbb N\quad \exists k,m\in \mathbb N \quad \text{s.t} \quad 2^k \log_2{n}<m<2^k \log_2{(n+1)}$$
And it's true, because if $\log_2{(n+1)}-\log_2{n}=\varepsilon $ then put $k$ so large such that $2^k\varepsilon>1$.
Remark : This method also works for any number $1<x$ other than $2$.
If $\log_x{(n+1)}-\log_x{n}=\varepsilon $ then there is a $k$ s.t $x^k\varepsilon>1$