Backbone - Is it possible to bind a change event to a model, except for one property?

You could use model.bind('change',function() {/*...*/}) and in the function use hasChanged to check the attributes: if(model.hasChanged('propIWantToExclude')) return;

Justin's answer above will return when 'propIWantToExclude' and some other attributes are changed together. You probably don't want to do that, so you should also look at the size of model.changedAttributes:

if(model.changedAttributes.length == 1 && model.hasChanged('attrIWantToExclude')) {
    return;
}