Cell color changing in Excel using C#

For text:

[RangeObject].Font.Color = System.Drawing.ColorTranslator.ToOle(System.Drawing.Color.Red);

For cell background

[RangeObject].Interior.Color = System.Drawing.ColorTranslator.ToOle(System.Drawing.Color.Red);

Note: This assumes that you will declare constants for row and column indexes named COLUMN_HEADING_ROW, FIRST_COL, and LAST_COL, and that _xlSheet is the name of the ExcelSheet (using Microsoft.Interop.Excel)

First, define the range:

var columnHeadingsRange = _xlSheet.Range[
    _xlSheet.Cells[COLUMN_HEADING_ROW, FIRST_COL],
    _xlSheet.Cells[COLUMN_HEADING_ROW, LAST_COL]];

Then, set the background color of that range:

columnHeadingsRange.Interior.Color = XlRgbColor.rgbSkyBlue;

Finally, set the font color:

columnHeadingsRange.Font.Color = XlRgbColor.rgbWhite;

And here's the code combined:

var columnHeadingsRange = _xlSheet.Range[
    _xlSheet.Cells[COLUMN_HEADING_ROW, FIRST_COL],
    _xlSheet.Cells[COLUMN_HEADING_ROW, LAST_COL]];

columnHeadingsRange.Interior.Color = XlRgbColor.rgbSkyBlue;

columnHeadingsRange.Font.Color = XlRgbColor.rgbWhite;