Determine asymmetric latencies in a network
To the best of my knowledge, asymmetric latencies -- especially "last mile" asymmetries -- cannot be automatically determined, because any network time synchronization protocol is equally affected by the same asymmetry, so you don't have a point of reference from which to evaluate the asymmetry.
If each endpoint had, for example, its own GPS clock, then you'd have a reference point to work from.
In Fast Measurement of LogP Parameters for Message Passing Platforms, the authors note that latency measurement requires clock synchronization external to the system being measured. (Boldface emphasis mine, italics in original text.)
Asymmetric latency can only be measured by sending a message with a timestamp ts, and letting the receiver derive the latency from tr - ts, where tr is the receive time. This requires clock synchronization between sender and receiver. Without external clock synchronization (like using GPS receivers or specialized software like the network time protocol, NTP), clocks can only be synchronized up to a granularity of the roundtrip time between two hosts [10], which is useless for measuring network latency.
No network-based algorithm (such as NTP) will eliminate last-mile link issues, though, since every input to the algorithm will itself be uniformly subject to the performance characteristics of the last-mile link and is therefore not "external" in the sense given above. (I'm confident it's possible to construct a proof, but I don't have time to construct one right now.)
There is a project called One-Way Ping (OWAMP) specifically to solve this issue. Activity can be seen in the LKML for adding high resolution timestamps to incoming packets (SO_TIMESTAMP, SO_TIMESTAMPNS, etc) to assist in the calculation of this statistic.
http://www.internet2.edu/performance/owamp/
There's even a Java version:
http://www.av.it.pt/jowamp/
Note that packet timestamping really needs hardware support and many present generation NICs only offer millisecond resolution which may be out-of-sync with the host clock. There are MSDN articles in the DDK about synchronizing host & NIC clocks demonstrating potential problems. Timestamps in nanoseconds from the TSC is problematic due to core differences and may require Nehalem architecture to properly work at required resolutions.
http://msdn.microsoft.com/en-us/library/ff552492(v=VS.85).aspx