Disable or lock zoom in Notepad++
Previously, I "Seriously ... cannot imagine a scenario where you're accidentally zooming." The hot keys involve Control-Mousewheel, or Control-Keypad-plus-or-minus. (If you'll excuse the description). These aren't near or similar to Control-C and Control-V. So you must be holding the control key while meaning to scroll in the document.
It was just pointed out to me that the trackpad might also be an issue (Jim himself said it was his mouse and he changed his mouse for resolving this). If it's the trackpad then you'd have to try to find a palm rejection sensitivity setting to tweak, which might not be available, or try remapping the zoom shortcuts, or try the plugin from Stan which disables zooming (I like that option a lot).
Anyway, it's been a while since I used it, but I'm told you can edit the shortcuts in the settings > shortcut mapper
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To disable mouse zooming, I wrote a small plugin for Notepad++ which does it.
Also, there is a 64-bit version of the plugin.
I don't have that issue. The only way it zooms is if you use CTRL-MouseWheel, or by CTRL-KP+ or CTRL-KP-. Most likely, you are trying to scroll the document when you still have CTRL held down (or active via StickyKeys.)
Best recommendation is to use CTRL-KP/ to reset the zoom.