graphlab-create 2.1 installation fails to uninstall 'certifi', a distutils installed project

There's a dependancy between pip 10.0.1 and certifi, try downgrading your pip to version 9.0.1 and then install graphlab.

To downgrade: pip install pip==9.0.1

Edit Aug 17th

Good point made in the comments below about pip being past version 20. Use virtual environments and trying ignoring the certifi component as suggest in the other answer.

Add the following to the pip command-line to ignore the uninstall:

 --ignore-installed certifi

Worked for me with Graphlab Create and Jupyter installed today.