How do I calculate the MD5 checksum of a file in Python?

In Python 3.8+ you can do

import hashlib

with open("your_filename.png", "rb") as f:
    file_hash = hashlib.md5()
    while chunk := f.read(8192):
        file_hash.update(chunk)

print(file_hash.digest())
print(file_hash.hexdigest())  # to get a printable str instead of bytes

On Python 3.7 and below:

with open("your_filename.png", "rb") as f:
    file_hash = hashlib.md5()
    chunk = f.read(8192)
    while chunk:
        file_hash.update(chunk)
        chunk = f.read(8192)

print(file_hash.hexdigest())

This reads the file 8192 (or 2¹³) bytes at a time instead of all at once with f.read() to use less memory.

---

Consider using hashlib.blake2b instead of md5 (just replace md5 with blake2b in the above snippets). It's cryptographically secure and faster than MD5.

hashlib methods also support mmap module, so I often use

from hashlib import md5
from mmap import mmap, ACCESS_READ

path = ...
with open(path) as file, mmap(file.fileno(), 0, access=ACCESS_READ) as file:
    print(md5(file).hexdigest())

where path is the path to your file.

Ref: https://docs.python.org/library/mmap.html#mmap.mmap

Edit: Comparison with the plain-read method.

from hashlib import md5
from mmap import ACCESS_READ, mmap

from matplotlib.pyplot import grid, legend, plot, show, tight_layout, xlabel, ylabel
from memory_profiler import memory_usage
from numpy import arange

def MemoryMap():
    with open(path) as file, mmap(file.fileno(), 0, access=ACCESS_READ) as file:
        print(md5(file).hexdigest())

def PlainRead():
    with open(path, 'rb') as file:
        print(md5(file.read()).hexdigest())

if __name__ == '__main__':
    path = ...
    y = memory_usage(MemoryMap, interval=0.01)
    plot(arange(len(y)) / 100, y, label='mmap')
    y = memory_usage(PlainRead, interval=0.01)
    plot(arange(len(y)) / 100, y, label='read')
    ylabel('Memory Usage (MiB)')
    xlabel('Time (s)')
    legend()
    grid()
    tight_layout()
    show()

path is the path to a 3.77GiB csv file.

In regards to your error and what's missing in your code. m is a name which is not defined for getmd5() function.

No offence, I know you are a beginner, but your code is all over the place. Let's look at your issues one by one :)

First, you are not using hashlib.md5.hexdigest() method correctly. Please refer explanation on hashlib functions in Python Doc Library. The correct way to return MD5 for provided string is to do something like this:

>>> import hashlib
>>> hashlib.md5("example string").hexdigest()
'2a53375ff139d9837e93a38a279d63e5'

However, you have a bigger problem here. You are calculating MD5 on a file name string, where in reality MD5 is calculated based on file contents. You will need to basically read file contents and pipe it though MD5. My next example is not very efficient, but something like this:

>>> import hashlib
>>> hashlib.md5(open('filename.exe','rb').read()).hexdigest()
'd41d8cd98f00b204e9800998ecf8427e'

As you can clearly see second MD5 hash is totally different from the first one. The reason for that is that we are pushing contents of the file through, not just file name.

A simple solution could be something like that:

# Import hashlib library (md5 method is part of it)
import hashlib

# File to check
file_name = 'filename.exe'

# Correct original md5 goes here
original_md5 = '5d41402abc4b2a76b9719d911017c592'  

# Open,close, read file and calculate MD5 on its contents 
with open(file_name, 'rb') as file_to_check:
    # read contents of the file
    data = file_to_check.read()    
    # pipe contents of the file through
    md5_returned = hashlib.md5(data).hexdigest()

# Finally compare original MD5 with freshly calculated
if original_md5 == md5_returned:
    print "MD5 verified."
else:
    print "MD5 verification failed!."

Please look at the post Python: Generating a MD5 checksum of a file. It explains in detail a couple of ways how it can be achieved efficiently.

Best of luck.