How to disable Xbox 360 "click for help" banner on Windows 10

Turning off XBoxStat.exe should work.

There should be an default installed UWP application called "Xbox Live" on your computer or something like that. This comes with the default install of Windows 10 and, amongst other things, provides a game overlay. I think that if you disable that overlay in the settings, you will no longer have this popup. However, I'm not 100% sure. If that option doesn't help, there might be a different option somewhere.