How to find sum of multiple columns in a table in SQL Server 2005?

Just as a regular SELECT?

SELECT 
   Val1, Val2, Val3,
   Total = Val1 + Val2 + Val3
FROM dbo.Emp

Or do you want to determine that total and update the table with those values?

UPDATE dbo.Emp
SET Total = Val1 + Val2 + Val3

If you want to have this total be current at all times - you should have a computed column in your table:

ALTER TABLE dbo.Emp
ADD CurrentTotal AS Val1 + Val2 + Val3 PERSISTED

Then you will always get the current total - even if the values change:

SELECT 
   Val1, Val2, Val3, CurrentTotal
FROM dbo.Emp

Easy:

SELECT 
   Val1,
   Val2,
   Val3,
   (Val1 + Val2 + Val3) as 'Total'
FROM Emp

or if you just want one row:

SELECT 
   SUM(Val1) as 'Val1',
   SUM(Val2) as 'Val2',
   SUM(Val3) as 'Val3',
   (SUM(Val1) + SUM(Val2) + SUM(Val3)) as 'Total'
FROM Emp

You must also be aware of null records:

SELECT  (ISNULL(Val1,0) + ISNULL(Val2,0) + ISNULL(Val3,0)) as 'Total'
FROM Emp

Usage of ISNULL:

ISNULL(col_Name, replace value)