Installing rpy2 for Python 3 using pip
There is no official support of windows.
There exists pre-compiled binaries (see: https://rpy2.github.io/doc/latest/html/overview.html#microsoft-s-windows-precompiled-binaries) but they are for an older release.
At the time of writing using the Linux subsystem available with Windows 10 might be the best options.
it works fine with conda on windows
conda install rpy2