iPhone Safari Web App opens links in new window
The other solutions here either don't account for external links (that you probably want to open externally in Safari) or don't account for relative links (without the domain in them).
The html5 mobile-boilerplate project links to this gist which has a good discussion on the topic: https://gist.github.com/1042026
Here's the final code they came up with:
<script>(function(a,b,c){if(c in b&&b[c]){var d,e=a.location,f=/^(a|html)$/i;a.addEventListener("click",function(a){d=a.target;while(!f.test(d.nodeName))d=d.parentNode;"href"in d&&(d.href.indexOf("http")||~d.href.indexOf(e.host))&&(a.preventDefault(),e.href=d.href)},!1)}})(document,window.navigator,"standalone")</script>
I found JavaScript solution in iWebKit framework:
var a=document.getElementsByTagName("a");
for(var i=0;i<a.length;i++)
{
a[i].onclick=function()
{
window.location=this.getAttribute("href");
return false
}
}