Keyboard shortcuts are not active in Visual Studio with Resharper installed

I would first try resetting all Visual Studio settings (Tools > Import and Export Settings > Reset all settings), then go to the Resharper > Options > Keyboard & Menus and re-apply the keyboard shortcut scheme.

I had to do something similar once.

This worked for me.

Setting to Resharper / Options / KeyBoard & Menus / None / Apply and Save

and then

Resharper / Options / KeyBoard & Menus / Set to Visual Studio / Apply and Save