Linux python3 - Can't open lib 'SQL Server'

I also recommend you install the ODBC Driver and then try to use pyodbc. I am assuming you are on an Ubuntu 15.04+ machine.

To install the ODBC Driver follow the following instructions:

sudo su
wget https://gallery.technet.microsoft.com/ODBC-Driver-13-for-Ubuntu-b87369f0/file/154097/2/installodbc.sh
sh installodbc.sh

Once you do that, install pyodbc using pip and try the following script:

import pyodbc
server = 'tcp:myserver.database.windows.net'
database = 'mydb'
username = 'myusername'
password = 'mypassword'
cnxn = pyodbc.connect('DRIVER={ODBC Driver 13 for SQL Server};SERVER='+server+';DATABASE='+database+';UID='+username+';PWD='+ password)
cursor = cnxn.cursor()
cursor.execute("SELECT @@version;")
row = cursor.fetchone()
while row:
    print row
    row = cursor.fetchone()

Let me know how that goes.

Cheers,
Meet

replace DRIVER={SQL Server} with DRIVER={/opt/microsoft/msodbcsql17/lib64/libmsodbcsql-17.0.so.1.1}

Download Dependencies depends on your platform, (for other OS Download your Dependencies)

This example for Ubuntu:

# sudo su 
curl https://packages.microsoft.com/keys/microsoft.asc | apt-key add -

#Download appropriate package for the OS version
#Choose only ONE of the following, corresponding to your OS version

#Ubuntu 14.04
# curl https://packages.microsoft.com/config/ubuntu/14.04/prod.list > /etc/apt/sources.list.d/mssql-release.list

#Ubuntu 16.04
curl https://packages.microsoft.com/config/ubuntu/16.04/prod.list > /etc/apt/sources.list.d/mssql-release.list

# #Ubuntu 18.04
# curl https://packages.microsoft.com/config/ubuntu/18.04/prod.list > /etc/apt/sources.list.d/mssql-release.list

# #Ubuntu 18.10
# curl https://packages.microsoft.com/config/ubuntu/18.10/prod.list > /etc/apt/sources.list.d/mssql-release.list

# #Ubuntu 19.04
# curl https://packages.microsoft.com/config/ubuntu/19.04/prod.list > /etc/apt/sources.list.d/mssql-release.list

exit
sudo apt-get update
sudo ACCEPT_EULA=Y apt-get install msodbcsql17
# optional: for bcp and sqlcmd
sudo ACCEPT_EULA=Y apt-get install mssql-tools
echo 'export PATH="$PATH:/opt/mssql-tools/bin"' >> ~/.bash_profile
echo 'export PATH="$PATH:/opt/mssql-tools/bin"' >> ~/.bashrc
source ~/.bashrc
# optional: for unixODBC development headers
sudo apt-get install unixodbc-dev

and then change,

DRIVER={/opt/microsoft/msodbcsql17/lib64/libmsodbcsql-17.0.so.1.1} 

DRIVER={ODBC Driver 17 for SQL Server}