LSOpenURLsWithRole() failes with error -10810 on Yosemite from within tmux

There is a solution/workaround for this:

• Update your version of reattach-to-user-namespace. This is used by tmux to execute programs. I use brew rather than macports, so I just did: brew update; brew upgrade reattach-to-user-namespace. Macports is likely to be able to do something similar.

• Add the following to your .tmux.conf file:

  set -g default-command "reattach-to-user-namespace -l /bin/bash"

Restart your tmux session and that should allow you to start programs from the command line.

Further information can be found at this github issue.

The issue is that tmux is changing the bootstrap to system domain when it shouldn't (see https://trac.macports.org/ticket/18357). Older versions of launchd worked around this bug in tmux, but the rewritten launchd in OS X Yosemite does not work around this tmux bug.

You will either need to wait for Apple to possibly release an update that works around the tmux bug or pester tmux developers to fix this bug in tmux that has been known for at least 6 years now.