Standard Model Proton Decay Rate
Electroweak instantons violate baryon number (and lepton number) by three units (all three generations participate in the 't Hooft vertex). This is explained in 't Hooft's original paper. As a result, the proton is absolutely stable in the standard model. The lightest baryonic state that is unstable to decay into leptons is $^3$He. The deuteron is unstable with regard to decay into an anti-proton and leptons.
The rate is proportional to $[\exp(-8\pi^2/g_w^2)]^2$, which is much smaller than the rates for proton decay that have been discussed in extensions of the standard model. Note that the decay $^3\mathrm{He}\to$ leptons involves virtual $(b,t)$ quarks, and the rate contains extra powers of $g_w$ in the pre-exponent (which does not matter much, given that the exponent is already very big).
Just to give a rough number, the lifetime is a typical weak decay lifetime (say, $10^{-8}$ sec), multiplied by the instanton factor $$ \tau = \tau_w \exp(16\pi^2/g_w^2)=\tau_w\exp(4\pi\cdot 137\cdot\sin^2\theta_W) = \tau_w\cdot 10^{187}\sim 10^{180}\, sec $$ where I have neglected many pre-exponetial factors which can be calculated, in principle, in the standard model.