virtualenv in PowerShell?

A quick work-around would be to invoke cmd and then run your activate.bat from within the cmd session. For example:

PS C:\my_cool_env\Scripts> cmd
Microsoft Windows [Version 6.1.7600]
Copyright (c) 2009 Microsoft Corporation.  All rights reserved.

C:\my_cool_env\Scripts>activate.bat
(my_cool_env) C:\my_cool_env\Scripts>

My original answer is now outdated. Now, just use activate.ps1 (rather than activate.bat) to activate from a Powershell environment.

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Original answer:

Here's a post that contains a Powershell script that allows you to run batch files that persistently modify their environment variables. The script propagates any environment variable changes back to the calling PowerShell environment.

Run the this command:

Set-ExecutionPolicy -ExecutionPolicy Bypass -Scope Process -Force

followed by:

./env/Scripts/activate.ps1

That's all

The latest version of virtualenv supports PowerShell out-of-the-box.

Just make sure you run:

Scripts\activate.ps1

instead of

Scripts\activate

The latter will execute activate.bat, which doesn't work on PowerShell.