Windows 10 shortcuts - onenote vs cortana

This turns off the Windows built in Win+S shortcut (removing it from Cortana), additionally a value of "SR" for instance would also disable Win+R (run).

[HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Advanced] "DisabledHotkeys"="S"

After setting this registry key restart Windows and Win+S will work for OneNote again.

I'm not really sure why so many people who don't know the actual answer to a question still choose to chime in, it's kind of frustrating how often I end up on Stack Exchange these days only to discover that people are providing misinformation or useless conjecture.

OneNote was updated in Oct 2013 and changed the shortcut to following on systems running Windows 8.1 and greater.

Windows + Shift + S

Source

Here is a crude animation showing that OneNote's screen-clip functionality still works on Windows 10 using the shortcut Windows+Shift+S. The only thing that is not shown, which I am unable to show, is the S being hightlighted on the on-screen keyboard since OneNote which is installed on my computer captures the shortcut before its displayed on the on-screen keyboard.

This worked for me:

First remove the Win+S binding from Search:

[HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Advanced] "DisabledHotkeys"="S"

Then get OneNote to bind to just Win+S again:

[HKEY_CURRENT_USER\SOFTWARE\Microsoft\Office\16.0\OneNote\Options\Other] "ScreenClippingShortcutKey"=0x00000053

credit to: http://answers.microsoft.com/en-us/office/forum/office_2013_release-onenote/onenote-screen-clipping-tool-hotkeys-in-windows-10/f454aa9d-c295-478c-8496-4146c1ba5876?page=2