Is it possible specify Xamarin Forms Entry Numeric Keyboard without comma or decimal point separator?

To restrict the Entry to only accept numbers you could use a Behavior or a Trigger.

Both of those will react to a user typing into them. So for your use, you could have the trigger or behavior look for any characters that are not numbers and remove them.

Something like this for a behavior (note that I wrote all this on SO and did not try compiling it, let me know if it does not work):

using System.Linq;
using Xamarin.Forms;

namespace MyApp {

    public class NumericValidationBehavior : Behavior<Entry> {

        protected override void OnAttachedTo(Entry entry) {
            entry.TextChanged += OnEntryTextChanged;
            base.OnAttachedTo(entry);
        }

        protected override void OnDetachingFrom(Entry entry) {
            entry.TextChanged -= OnEntryTextChanged;
            base.OnDetachingFrom(entry);
        }

        private static void OnEntryTextChanged(object sender, TextChangedEventArgs args) 
        {

            if(!string.IsNullOrWhiteSpace(args.NewTextValue)) 
            { 
                 bool isValid = args.NewTextValue.ToCharArray().All(x=>char.IsDigit(x)); //Make sure all characters are numbers

                ((Entry)sender).Text = isValid ? args.NewTextValue : args.NewTextValue.Remove(args.NewTextValue.Length - 1);
            }
        }


    }
}

Then in your XAML:

<ContentPage xmlns="http://xamarin.com/schemas/2014/forms"
         xmlns:x="http://schemas.microsoft.com/winfx/2009/xaml"
         xmlns:local="clr-namespace:MyApp;assembly=MyApp"> <!-- Add the local namespace so it can be used below, change MyApp to your actual namespace -->

  <Entry x:Name="AgeEntry"
         VerticalOptions="FillAndExpand"
         HorizontalOptions="FillAndExpand"
         Keyboard="Numeric">
    <Entry.Behaviors>
      <local:NumericValidationBehavior />
    </Entry.Behaviors>
  </Entry>

</ContentPage>

To me the simple solution is just to add a TextChanged handle to the Entry (this is UI specific code so does not break MVVM)

   <Entry Text="{Binding BoundValue}" Keyboard="Numeric" TextChanged="OnTextChanged"/>

Then in code behind

    private void OnTextChanged(object sender, TextChangedEventArgs e)
    {
        //lets the Entry be empty
        if ( string.IsNullOrEmpty(e.NewTextValue) ) return;

        if ( !double.TryParse(e.NewTextValue, out double value) )
        {
            ((Entry) sender).Text = e.OldTextValue;
        }
    }

Change in int.Parse if need an integer

I was facing this too, but the best way to implement this is through behaviors, here is an article which shows you in detail how to implement this and even more, like limiting the value of the number entered to a given value you set in your XAML.