Is it possible to disable anti-aliasing in CSS when using @font-face with pixel fonts?

Font rendering is done by the operating system and browser, so, as of yet, I believe there is little that you can do with CSS. There may be some proposed CSS rules in discussion (I've seen mention "font-smooth" or something like that), but nothing in CSS3, as far as I know, and definitely nothing in CSS2.

This question is old, so just wanted to give an update.

Based on caniuse.com, there's a CSS property for it but has been removed from the CSS3 specification drafts. So it is not a standard solution. Some Webkit, Firefox & Opera browsers support it but it is inconsistent. It mostly works for desktop and Mac OS users

-webkit-font-smoothing: none || antialiased || subpixel-antialiased
-moz-osx-font-smoothing: auto || inherit || unset || grayscale
font-smoothing: auto || inherit || unset || grayscale

I had similar problem today and it seems that although font-smooth does not work in contemporary Firefox* adding some filter does:

filter: contrast(1);

Yet it seems to be a bit hacky to disable anti-aliasing with filter. By the way it does not cause to completely disable anti-aliasing just causes it to be applied somehow differently so bitmap fonts render correctly. On the other hand it breaks rendering of non-bitmap fonts.

 * Tested on Fixedsys from http://doir.ir/fixedsys/demo.html, on Iceweasel 38.40.0, on Debian 8.