Is there a way to install Valgrind on Catalina?

Ok. I've found a way to use Valgrind on Catalina. Here's a link to my guide for how https://github.com/john-yohan-park/Valgrind_Catalina

Works amazingly!! see https://github.com/LouisBrunner/valgrind-macos/issues/5.

Not Homebrew, you need to compile it from source, but it's not so difficult.

1. git clone https://github.com/LouisBrunner/valgrind-macos.git
2. cd valgrind
3. sudo ./autogen.sh
4. sudo ./configure --prefix=/where/you/want/it/installed --enable-only64bit
5. copy the [contents][1] to ./coregrind/m_mach/mach_basics.c
6. sudo make 
7. sudo make install

enjoy!

Currently, no. The repo you link has an issue raised about Catalina compatibility. As you also show, the brew package has its own problems as well. Official valgrind only supports 10.12.

You'll just have to wait, or containerize it. Although if you containerize valgrind, you would likely need a compatible build container as well.