how to make discord.js bot remove a reaction code example
Example: discord.js remove reaction
Since this question is getting a lot of attraction, I decided to post what worked for me
Remove Specific User's Specific Reaction
const msg = await channel.messages.fetch(MessageID);
msg.reactions.resolve("REACTION EMOJI,
REACTION OBJECT OR REACTION ID").users.remove("ID OR OBJECT OF USER TO REMOVE");
Note: If using an older version of discord.js, simply replace channel.messages.fetch with channel.fetchMessage