select2 destroy and clear code example

Example 1: select2 clear options

Remove the selected options : 
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$('#mySelect2').val(null).trigger('change');

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Completly remove the select2 initialization :
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$('#payment_method').html('').select2({data: [{id: '', text: ''}]});

Example 2: select2 destroy

if ($('#mySelect2').hasClass("select2-hidden-accessible")) {
    // Select2 has been initialized
    $('#mySelect2').select2('destroy');
}