Last two digits of $2^{1000}$ via Chinese Remainder Theorem?
You have that $2^{20}\equiv 1\pmod{25}$ (thanks to Euler's Theorem), and therefore that $2^{1000} = (2^{20})^{50}\equiv 1\pmod{25}$.
For the congruence modulo $4$ you don't even need to invoke Euler's Theorem; you can just note that since $2^2\equiv 0\pmod{4}$, then $2^{1000}\equiv 0 \pmod{4}$. So the system of congruences you have is: $$\begin{align*} x &\equiv 1\pmod{25}\\ x &\equiv 0 \pmod{4} \end{align*}$$ There is one and only one number modulo 100 that satisfies both these congruences by the Chinese Remainder Theorem (it is $x\equiv 76\pmod{100}$). Since $2^{1000}$ satisfies both congruences, the CRT tells you that...
(The use of Euler's Theorem was just to simplify the computation of $2^{1000}$ modulo $25$; but to find out $2^{1000}$ modulo $4$, there is no need to simplify it, it is already very simple.)
By $\, ab\,\bmod\, \color{#90f}{ac}\, =\ a\,(b\bmod c)\, =\, $ mod Distributive Law $ $ & $\!\overbrace{\color{#c00}{2^{\large 10}}\! = 1024\equiv -1\pmod{\!25}}^{\!\!\!\!\!\Large {\rm or}\ \, \color{#c00}{2^{\LARGE 20}\equiv\ 1}\ \ {\rm by\ Euler\ \phi\ (totient)}}\,$
$\ \ 2^{\large 20J}\!\! \bmod \color{#90f}{100}\, =\, 4\!\!\!\!\!\!\!\!\!\!\!\!\!\!\!\underbrace{\left[\dfrac{\color{#c00}{2}^{\large\color{#c00}{20}J}}4\!\bmod 25\right]}_{\large\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \equiv\ {\small\dfrac{\color{#c00}1}4}\equiv\ {\small\dfrac{-24}4}\,\ \equiv\ -6\ \ \equiv\ \ \color{#0a0}{19}}\!\!\!\!\!\!\!\!\!\!\!\!\!\!\!\! = 4[\color{#0a0}{19}] = 76$ $\, \left\{\!\begin{align} &\text{mDL = ${\it operational}$ version of $\rm\small CRT$}\\ &\!\text { as explained in prior linked answer.}\end{align}\right.$
Remark $ $ Above used $\,4\mid \color{#c00}2^{\large \color{#c00}{20}J}\ $ by $\,J\ge 1\,\ [J=50\ \ \rm in\ OP].\ $ Another example from here
$\ \ 35^{\large 73} 53^{\large 25}\bmod 100\, =\, 25\left[\dfrac{35^{\large 73} 53^{\large 25}}{25}\bmod 4\right] = 25\overbrace{\left[\dfrac{(-1)^{\large 73} 1^{\large 25}}{1}\bmod 4\right]}^{\ \ \ \large \equiv\ -1\ \equiv\ \color{#c00}{ 3}\ \pmod{\!4}^{\phantom{|}}} = 25[\color{#c00}3] $