List comprehension on a nested list?

Here is how you would do this with a nested list comprehension:

[[float(y) for y in x] for x in l]

This would give you a list of lists, similar to what you started with except with floats instead of strings. If you want one flat list then you would use [float(y) for x in l for y in x].

Here is how to convert nested for loop to nested list comprehension:

Here is how nested list comprehension works:

            l a b c d e f
            ↓ ↓ ↓ ↓ ↓ ↓ ↓
In [1]: l = [ [ [ [ [ [ 1 ] ] ] ] ] ]
In [2]: for a in l:
   ...:     for b in a:
   ...:         for c in b:
   ...:             for d in c:
   ...:                 for e in d:
   ...:                     for f in e:
   ...:                         print(float(f))
   ...:                         
1.0

In [3]: [float(f)
         for a in l
   ...:     for b in a
   ...:         for c in b
   ...:             for d in c
   ...:                 for e in d
   ...:                     for f in e]
Out[3]: [1.0]

For your case, it will be something like this.

In [4]: new_list = [float(y) for x in l for y in x]

Not sure what your desired output is, but if you're using list comprehension, the order follows the order of nested loops, which you have backwards. So I got the what I think you want with:

[float(y) for x in l for y in x]

The principle is: use the same order you'd use in writing it out as nested for loops.