Magento 2.1.2, Remove "region" from the Address
If you want disable Region from the address, you have to set below option like.
State is Required for : remove all selected country from here.
Allow to Choose State if It is Optional for Country : Set it as "No"
You can also remove it from "add new address" in customer account.
Copy file form vendor/magento/module-customer/view/frontend/templates/address/edit.phtml
add it in your theme. You can remove region from here for customer add new address.
Save configuration, remove var folder.