mysql don't insert if already exists some column onluy code example

Example 1: mysql insert into if not exists

INSERT INTO table_name (firstname, lastname)
SELECT 'NEW FIRSTNAME', 'NEW LASTNAME'
FROM DUAL
WHERE NOT EXISTS(
    SELECT 1
    FROM table_name
    WHERE firstname = 'NEW FIRSTNAME' AND lastname = 'NEW LASTNAME'
)
LIMIT 1;

Example 2: php sql insert into if not exists

INSERT IGNORE INTO `transcripts`
SET `ensembl_transcript_id` = 'ENSORGT00000000001',
`transcript_chrom_start` = 12345,
`transcript_chrom_end` = 12678;